The compound is efficacious but does it have a window of safety?Establishing a Therapeutic Index (TI), which is appropriate for your clinical indication, is essential to compound selection for IND-enabling studies.
VIVOPATH looks to assess safety of a compound in all studies that we conduct from the earliest single dose PK study.We report clinical observations from all in vivo studies at no extra cost to the client and can conduct longer term dosing studies for assessment of compound toxicity.The following are readouts that we can provide to assess toxicity:
Clinical chemistry
Hematology
Urinalysis
Necropsy
Histopathology
Please contact us if you are in need of toxicity assessment.
